Adam Jones has been ruled out of Wales's Autumn Test series with a knee injury.
The highly-rated prop, who limped off during the Ospreys' Heineken Cup defeat to Leicester on Sunday, faces up to 10 weeks on the sidelines.
Jones, 31, will miss games against Argentina, Samoa, New Zealand and Australia.
Scarlets prop Samson Lee is expected to replace Jones in the Red Dragons squad.
Jones has won 83 caps at senior international level.
