Manchester United are reportedly expecting Luke Shaw to be on the sidelines for the next 10 weeks, which has driven their desire to sign a new left-back before the end of the transfer window.
The Red Devils had already been short at left-back, with Tyrell Malacia on the sidelines due to a muscular problem, and it was then confirmed after the clash with Tottenham Hotspur that Shaw was facing a spell out of action due to a muscular issue of his own.
Man United have not set an exact timeframe when it comes to the England international, but according to the Daily Mail, he is likely to be on the sidelines for the next 10 weeks.
Shaw is not expected to need any surgical intervention, but it is a long-term issue, while Malacia is not expected to be available for selection until at least October.
Diogo Dalot played at left-back against Nottingham Forest on Saturday, and the Portugal international will continue to be an option in that area of the field.
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However, the club are said to be closing in on the loan signing of Sergio Reguilon from Tottenham Hotspur.
The Spaniard, who spent last season on loan at Atletico Madrid, has allegedly been given permission to travel to Old Trafford to undergo a medical with the Red Devils.
Should the deal move quickly in the coming hours, there is a chance that the left-back could be on the bench for Sunday's Premier League clash with Arsenal at the Emirates Stadium.
Chelsea's Marc Cucurella is also believed to have been considered, but a deal for the former Brighton & Hove Albion left-back at this stage is believed to be off the table.
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Man United have also been hit with the news that Raphael Varane is facing a spell on the sidelines with a problem that he picked up in the 3-2 win over Forest last weekend.
Harry Maguire's chances of leaving Old Trafford before the end of the window have seemingly ended due to Varane's issue.
However, Maguire - named in Gareth Southgate's latest England squad - remains behind Victor Lindelof in the pecking order, so he is not expected to start against Arsenal on Sunday.
Man United are set to be busy in the latter stages of the window, with the club also working on deals for Fiorentina's Sofyan Amrabat and Fenerbahce's Altay Bayindir.