Italian champions Juventus will begin the defence of their Serie A title with a home clash against Udinese.
The Bianconeri will be looking for a fifth straight Scudetto after winning a league and cup double last season.
Meanwhile, their title rivals Roma face a trip to Hellas Verona, while Napoli are also away to Sassuolo.
AC Milan have been handed a potentially tricky tie against Fiorentina, with their city rivals Inter Milan hosting Atalanta BC at San Siro.
Elsewhere, Frosinone will begin their first top flight campaign at home to Torino, and fellow new boys Carpi will travel to Sampdoria.
Serie A opening fixtures
Empoli vs. AC Chievo Verona
Fiorentina vs. AC Milan
Frosinone vs. Torino
Hellas Verona vs. Roma
Inter Milan vs. Atalanta BC
Juventus vs. Udinese
Lazio vs. Bologna
Palermo vs. Genoa
Sampdoria vs. Carpi
Sassuolo vs. Napoli
All games to be played on the weekend of August 23.