Inter Milan make the trip to Juventus knowing that they can ill afford another defeat if they wish to remain competitive in the Serie A title race.
After losing to Lazio in their last domestic encounter, Antonio Conte's side sit six points adrift of the league leaders, albeit with a game in hand.
However, having reached the Europa League last 16 since that setback, Inter will have regained some confidence ahead of the visit to Turin.
Here, Sports Mole predicts how the visitors could line up against Maurizio Sarri's outfit.
Out: Roberto Gagliardini (bone), Stefano Sensi (foot)
The most notable selection news is the return to domestic action of goalkeeper Samir Handanovic, who has now recovered from a hand injury.
While the established back three will remain the same, Ashley Young is expected to get the nod in the left wing-back position.
Although Christian Eriksen has impressed in the Europa League, the Dane has made less of an impression in Serie A, something which Conte will take into account this weekend.
With that in mind and given the magnitude of the fixture, Matias Vecino is likely to be selected in a midfield three alongside Marcelo Brozovic and Nicolo Barella.
Despite having completed the full 90 minutes against Ludogorets Razgrad on Thursday, Alexis Sanchez is expected to drop back down to the substitutes' bench, allowing Lautaro Martinez to partner Romelu Lukaku.
> Click here to see how Juventus could line up for this contest
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