France captain Hugo Lloris has vowed to 'hit Spain where it hurts' when they meet in Tuesday's World Cup qualifier.

Les Bleus will be looking for a positive result in Madrid against the World and European champions following their shock 1-0 friendly defeat to Japan on Friday.

"It could be difficult, but we have to be together, and everyone has to put in a huge effort and hit them where it hurts," Lloris told reporters. "We will certainly have our chances, and we cannot let them pass."

Spain currently lead France in Group I on goal difference after both sides picked up wins in their opening two matches.