Vitesse vs. Cambuur (Sunday, 11.15am)
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Vitesse will be looking to take one step further towards securing their top-flight status when they welcome Cambuur to GelreDome on Sunday morning.
For the visitors, this weekend's clash is nothing more than a dead rubber, having already suffered relegation from the top tier of Dutch football.
We say: Vitesse 2-1 Cambuur
Despite suffering a bump in the road last time out, Vitesse will back themselves to get back to winning ways against a Cambuur side who have been underwhelming this term. We are tipping the home side to get the job done come the sound of the full-time whistle.
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Groningen vs. Ajax (Sunday, 1.30pm)
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Ajax square off against Groningen on Sunday afternoon knowing that only victory will realistically do if they wish to retain hope of a top-two finish in the Eredivisie table.
While Ajax have struggled this campaign, it is not in comparison to their hosts who have already been relegated to the second tier.
We say: Groningen 0-2 Ajax
Despite the gulf in class between these two clubs, that will not necessarily lead to a straightforward afternoon for the visitors. Nevertheless, it would come as a surprise if Ajax did not prevail, potentially with a goal in either half.
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Feyenoord vs. Go Ahead Eagles (Sunday, 3.45pm)
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Feyenoord play host to Go Ahead Eagles on Sunday afternoon knowing that victory will secure the Eredivisie title with two games to spare.
At a time when the home side sit eight points clear at the top of the standings, the visitors have recently moved into 11th spot courtesy of a three-game undefeated streak.
We say: Feyenoord 3-0 Go Ahead Eagles
Despite the glory which awaits them, do not expect a tense performance from Feyenoord. They will relish this occasion and we expect a commanding performance to boot, one which may deliver a number of goals and a clean sheet.
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AZ vs. Emmen (Sunday, 7.00pm)
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AZ Alkmaar will continue their hunt for a top-three finish in the Eredivisie when they face off against Emmen at the AFAS Stadion on Sunday evening.
For the away side, pulling further clear of relegation danger will be the major target as they currently sit outside the drop zone by the skin of their teeth.
We say: AZ Alkmaar 2-0 Emmen
With one eye on their continental commitment, AZ could elect to rest several key players for this weekend's contest, but they should still have enough about themselves to secure all three points in a relatively comfortable manner.
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PSV vs. Sittard (Sunday, 7.00pm)
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PSV Eindhoven take on Fortuna Sittard at the Philips Stadion on Sunday afternoon, in the latest round of Eredivisie fixtures.
The hosts are still technically able to win the title at the time of writing, but only if Feyenoord fail to win the earlier kickoff, while the visitors are in 12th place.
We say: PSV Eindhoven 3-0 Fortuna Sittard
PSV Eindhoven have a fantastic record against Fortuna Sittard, having won 13 and drawn two of the last 15 meetings between the two sides, and they should have no trouble cruising to an easy victory on Sunday.
Van Nistelrooy's side have the best home record in the division, collecting 40 points in 15 games, and they are very likely to take all three points in their penultimate match at the Philips Stadion.