Tottenham Hotspur will play Inter Milan or CFR Cluj in the last 16 of the Europa League if they can progress past French side Lyon.
Andre Villas Boas's men will face a tough test to overcome the Ligue 1 side in the round of 32 but if they do move through to the round of 16, they could face a trip to the Italian giants, whom they played in their debut season of the Champions League two years ago.
Chelsea face a potential trip to Holland to face Ajax if they can beat Sparta Prague.
Liverpool will play Basle or FC Dnipro if they can secure a safe passage past Zenit St. Petersburg, while Newcastle United face a tie against Anzhi Makhachkala or Hannover 96 if they can get past Metalist Kharkiv.
Round of 16 in full
Ajax or Steaua Bucharest vs. Sparta Prague or Chelsea
Basle or Dnipro vs. Zenit or Liverpool
Levante or Olympiakos vs. Atletico Madrid or Rubin Kazan
Tottenham or Lyon vs. Inter or Cluj
Stuttgart or Genk vs. Borussia Monchengladbach or Lazio
Anzhi or Hannover vs. Newcastle or Metalist
Bayer Leverkusen or Benfica vs. Dynamo Kiev or Bordeaux
Napoli or Viktoria Plzen vs. BATE or Fenerbahce