Bayern vs. FC Koln (Saturday, 2.30pm)
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Bayern Munich could see their historic 11-year hold on the Bundesliga title come to an end when they take on relegation candidates FC Koln on Saturday afternoon.
The travelling fans will also be under pressure this weekend with their side running out of time to accumulate points to secure their status in the top flight.
We say: Bayern Munich 3-1 FC Koln
While Koln have been very poor this season, they have been difficult to beat on the road recently and should find the net in this one. The Bavarians are likely to see their hold on the Bundesliga Meisterschale come to an end this weekend, but we feel that they will win this match comfortably and force Die Werkself to beat Werder Bremen on Sunday.
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RB Leipzig vs. Wolfsburg (Saturday, 2.30pm)
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RB Leipzig will look to maintain their place in the top four of the Bundesliga standings when they take on a stuttering Wolfsburg at Red Bull Arena on Saturday afternoon.
The hosts will be out for revenge here, having already lost to this opponent twice this season, with the first defeat knocking them out of the DFB-Pokal while the second was in the reverse fixture back in November.
We say: RB Leipzig 2-0 Wolfsburg
While RB Leipzig have lost the last two games against this opponent, both of those games were at Volkswagen Arena. Back at home and in good form, we feel the hosts will take all three points in this one.
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Mainz vs. Hoffenheim (Saturday, 2.30pm)
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Mainz 05 will continue their quest to stave off relegation from the Bundesliga when they take on TSG Hoffenheim at the Mewa Arena on Saturday afternoon.
The hosts head into gameweek 28 in the relegation playoff spot with 23 points while the visitors moved up to eighth place last week, now on 36 points with six league games left to play.
We say: Mainz 05 2-2 Hoffenheim
While Mainz have struggled for consistency for the majority of the season, they are unbeaten at home under Bo Henriksen and won their last two games without conceding. Matches involving these two sides have not been short of goals of late and we are expecting another high-scoring encounter here, though we feel that there will be nothing to split them at the final whistle.
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Borussia M'bach vs. Dortmund (Saturday, 2.30pm)
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Borussia Dortmund will be hoping to move back into the top four places in the Bundesliga when they make the short trip to Borussia-Park to face Borussia Monchengladbach on Saturday night.
The hosts are currently in 11th place in the German top flight with 31 points after 28 games, while the visitors are the first side below the Champions League qualification spots with six games left to play.
We say: Borussia Monchengladbach 2-3 Borussia Dortmund
While Dortmund will have one eye on their midweek fixture against Atletico Madrid, they cannot afford to give up any more points in the league, with a spot in next season's Champions League still hanging in the balance.
Each of the last four matches between these sides have ended with six goals scored, and we are expecting another high-scoring affair here, though we feel that the visitors will be the ones to come out on top.
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VfL Bochum vs. Heidenheim (Saturday, 2.30pm)
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Relegation-threatened VfL Bochum welcome Heidenheim to Vonovia Ruhrstadion in the Bundesliga on Saturday afternoon.
The hosts are winless in six consecutive matches heading into this match, while the visitors ended a six-game winless run in their last match.
We say: VfL Bochum 1-2 Heidenheim
Bochum's winless run and managerial uncertainty collide with a confident Heidenheim. Home advantage could see Bochum fight, but the visitors boast momentum. We expect a close match, with Heidenheim edging it due to their recent confidence-boosting victory over Bayern.
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Stuttgart vs. Frankfurt (Saturday, 5.30pm)
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Stuttgart could move into the top two in the Bundesliga standings when they take on Eintracht Frankfurt at the MHPArena on Saturday evening.
The hosts are on 60 points after 28 games and are level with Bayern Munich in second place, while the visitors are sixth and currently on 42 points, six points clear of seventh-placed Augsburg.
We say: Stuttgart 3-1 Eintracht Frankfurt
Stuttgart are enjoying their best-ever season in the top flight up to this point and are carrying all the momentum, having avoided defeat in 10 consecutive league games. Die Roten are also unbeaten in their last nine games at home, including six wins and we feel they will be able to add to that tally with another victory in this one.