England head coach Stuart Lancaster has made five changes to his starting lineup for Saturday's encounter against Samoa at Twickenham.
Bath fly-half George Ford will make his first start at senior international level and he will take the number 10 jersey from Owen Farrell, who instead will move to inside centre at the expense of Kyle Eastmond.
Elsewhere, Rob Webber, James Haskell, Ben Morgan and scrum-half Ben Youngs have replaced Dylan Hartley, Tom Wood, Billy Vunipola and Danny Care respectively.
England: 15 Mike Brown; 14 Anthony Watson, 13 Brad Barritt, 12 Owen Farrell, 11 Jonny May; 10 George Ford, 9 Ben Youngs; 1 Joe Marler, 2 Rob Webber, 3 David Wilson, 4 Dave Attwood, 5 Courtney Lawes, 6 James Haskell, 7 Chris Robshaw, 8 Ben Morgan