Injury-hit Manchester United have given 19-year-old Paddy McNair his full debut against West Ham United this afternoon as the club look to bounce back from their shock defeat to Leicester City.
McNair partners Marcos Rojo in central defence, with Phil Jones, Chris Smalling and Jonny Evans injured and Tyler Blackett suspended.
West Ham United start with Enner Valencia and Diafra Sakho up top, while Mark Noble misses out.
Cheikhou Kouyate, Kevin Nolan, Matt Jarvis, Andy Carroll and Joey O'Brien are all sidelined with ongoing issues.
Manchester United: De Gea; Rafael, Shaw, Rojo, McNair; Di Maria, Herrera, Blind, Rooney, van Persie, Falcao
West Ham United: Adrian; Reid, Cresswell, Tomkins, Downing; Sakho, Demel, Amalfitano, Poyet, Song, Valencia
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