Tottenham Hotspur manager Antonio Conte should be without no fewer than four players for Thursday's crucial North London derby with Arsenal in the Premier League.
Matt Doherty, Japhet Tanganga and Oliver Skipp are all continuing their long-term recoveries, and Conte is not optimistic about Sergio Reguilon's chances of returning from a groin problem before the season is over.
However, none of the quartet would be likely to force their way into the team at present, with Conte sure to stick with an unchanged starting XI from the draw at Liverpool if he can avoid making any enforced alterations.
Cristian Romero has slotted into the backline seamlessly and will once again protect Hugo Lloris alongside Eric Dier and Ben Davies, who both played out of their skin at Anfield.
Emerson Royal and Ryan Sessegnon will bomb down the flanks, while Pierre-Emile Hojbjerg and Rodrigo Bentancur form their effective midfield pairing for the Lilywhites.
Dejan Kulusevski and Son Heung-min should certainly fancy their chances against a shaky Arsenal backline, with Tottenham needing to avoid defeat if they are to keep their top-four hopes alive.
Harry Kane heads into Thursday's clash boasting a record 11 goals in North London derbies, although he has failed to net in his last two appearances against the Gunners.
Tottenham possible starting lineup: Lloris; Romero, Dier, Davies; Emerson, Hojbjerg, Bentancur, Sessegnon; Kulusevski, Kane, Son
> Click here to see how Arsenal could line up for the derby
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